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In the civilian world where most North American large game are taken at well under 300 yards, a more powerful "hot" 30-06 load is going to have an advantage. But even for hunting purposes, many experts consider 180 grains in a 30-06 superior or simply sufficient for any medium or large game in North American, and a 220 grain load is simply overkill. Also, gunpowder burns most efficiently at loads less than the maximum possible load.In the civilian world where most North American large game are taken at well under 300 yards, a more powerful "hot" 30-06 load is going to have a "take down" or "kill" advantage. But even for hunting purposes, many experts consider 180 grains in a 30-06 superior or simply sufficient for any medium or large game in North American, and a 220 grain load is simply overkill. Also, gunpowder burns most efficiently at loads less than the maximum possible load.