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Identify the serial port for the device. in /dev you should see the following: /dev/ttyUSB0 then identify and inspect the port with the device connected and on.tty -F /dev/ttyUSB0 -aOnce you know it exists and you can communicate with the device through Linux (the host operating system) you can continue. Make sure your user (you) are a member of the dialout group sudo adduser nicolep dialoutWine (current versions >3) detects ports when it is run. You should look in ~/.wine/dosdevices folder for links to tty ports.Following their instructions sudo vi ~/.wine/system.reg Look for "Serialcomm" and '''E486: Pattern not found''' rendering usercomp.com advice absolutely useless. == references ==* https://usercomp.com/news/1036506/application-under-wine-cannot-access-any-serial-ports* https://www.onetransistor.eu/2015/12/wine-serial-port-linux.html