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For other distributions users have reported that choosing "OpenGL" is the solution. You may have to try different options. The "XVideo output (XCB)" option has been verified to resolve the problem on Mint 20 with AMD GPU.For other distributions users have reported that [https://askubuntu.com/questions/1250477/vlc-is-still-running-even-i-closed-it-already-how-to-i-close-it choosing OpenGL] is the solution. You may have to try different options. The "XVideo output (XCB)" option has been verified to resolve the problem on Mint 20 with AMD GPU.