MSG intake study
In conclusion, our studies suggest that the headaches caused by MSG intake may be related to its injurious effect on brain neurons. Although the brain does not register pain because of the lack of nociceptors, the increase of intracranial pressure due to cell swelling is well known to cause headaches. There are some possible ways, e.g. taking Vitamin C or pre-exposure to a low dose of MSG, that may either prevent or reduce the side effects of MSG.